Publications Le 07 Déc 2020 Publications Filtrer nos publications par : Année202420232022202120202019201820172016201520142013201220112010200920082007200620052004200320022001 2009 PPACK-Desmodus rotundus salivary plasminogen activator (cDSPAalpha1) prevents the passage of tissue-type plasminogen activator (rt-PA) across the blood-brain barrier and neurotoxicity. Consulter 2009 [Cellular microparticles, potential useful biomarkers in the identification of cerebrovascular accidents]. The clinical utility of biomarkers depends on their ability to identify high-risk individuals in order to establish preventive, diagnostic or (…) Consulter 2009 [Cerebral ischemia (2), How to neutralize the neurotoxic effects of tPA]. Consulter 2010 NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity. Although the molecular bases of its actions remain debated, tissue-type plasminogen activator (tPA) is a paradoxical brain protease, as it (…) Consulter 2010 The NR1 subunit of NMDA receptor regulates monocyte transmigration through the brain endothelial cell barrier. Normal neuronal functioning is dependent on the blood-brain barrier. This barrier is confined to specialized brain endothelial cells lining the (…) Consulter 2010 Tissue-type plasminogen activator induces plasmin-dependent proteolysis of intracellular neuronal nitric oxide synthase. Despite its pro-fibrinolytic activity, tPA (tissue plasminogen activator) is a serine protease known to influence a number of physiological and (…) Consulter Pages: 123456789101112131415161718192021222324252627282930313233343536373839404142434445464748495051525354555657585960616263646566676869707172737475767778798081828384858687888990919293Load More Retour