Publications Le 07 Déc 2020 Publications Filtrer nos publications par : Année2025202420232022202120202019201820172016201520142013201220112010200920082007200620052004200320022001 2009 Age and albumin D site-binding protein control tissue plasminogen activator levels: neurotoxic impact. Recombinant tissue-type plasminogen activator (tPA) is the fibrinolytic drug of choice to treat stroke patients. However, a growing body of (…) Consulter 2009 Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: an in vitro study. NXY-059, a polar compound with limited transport across the blood-brain barrier, has demonstrated neuroprotection in several animal models of acute (…) Consulter 2009 PPACK-Desmodus rotundus salivary plasminogen activator (cDSPAalpha1) prevents the passage of tissue-type plasminogen activator (rt-PA) across the blood-brain barrier and neurotoxicity. Consulter 2009 [Cellular microparticles, potential useful biomarkers in the identification of cerebrovascular accidents]. The clinical utility of biomarkers depends on their ability to identify high-risk individuals in order to establish preventive, diagnostic or (…) Consulter 2009 [Cerebral ischemia (2), How to neutralize the neurotoxic effects of tPA]. Consulter 2010 NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity. Although the molecular bases of its actions remain debated, tissue-type plasminogen activator (tPA) is a paradoxical brain protease, as it (…) Consulter Pages: 123456789101112131415161718192021222324252627282930313233343536373839404142434445464748495051525354555657585960616263646566676869707172737475767778798081828384858687888990919293949596Load More Retour