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Le 07 Déc 2020

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2000

Serine protease inhibitors: novel therapeutic targets for stroke?

Although the thrombolytic activity of tissue-type plasminogen activator (t-PA) may be beneficial in the acute treatment of stroke, recent studies (…)

Consulter

2000

Neurons and astrocytes express EPO mRNA: oxygen-sensing mechanisms that involve the redox-state of the brain.

Erythropoietin (Epo), the major hormone controlling the hypoxia-induced increase in the number of erythrocytes, has also a functional role in (…)

Consulter

1999

A transforming growth factor-beta antagonist unmasks the neuroprotective role of this endogenous cytokine in excitotoxic and ischemic brain injury.

Various studies describe increased concentrations of transforming growth factor-beta (TGF-beta) in brain tissue after acute brain injury. However, the role (…)

Consulter

1999

Transforming growth factor-beta1 as a regulator of the serpins/t-PA axis in cerebral ischemia.

The tissue type plasminogen activator (t-PA) is a serine protease that is involved in neuronal plasticity and cell death induced (…)

Consulter

1998

Glycosyl phosphatidylinositol (GPI)/inositolphosphate glycan (IPG): an intracellular signalling system involved in the control of thyroid cell proliferation.

In porcine thyrocytes, TSH alone does not induce cell growth. Recently, it has been demonstrated that acute stimulation by TSH (…)

Consulter

1998

Up-regulation of a serine protease inhibitor in astrocytes mediates the neuroprotective activity of transforming growth factor beta1.

Serine proteases play a key role in the fundamental biology of the central nervous system (CNS), and recent data suggest (…)

Consulter

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