Publications

Le 07 Déc 2020

Publications

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2018

Worse Outcome in Stroke Patients Treated with rt-PA Without Early Reperfusion: Associated Factors.

Based on preclinical studies suggesting that recombinant tissue plasminogen activator (rt-PA) may promote ischemic brain injuries, we investigated in patients (…)

Consulter

2018

Optimized tPA: A non-neurotoxic fibrinolytic agent for the drainage of intracerebral hemorrhages.

Intracerebral hemorrhage (ICH) is the most severe form of stroke. Catheter-delivered thrombolysis with recombinant tissue-type plasminogen activator (rtPA) for the (…)

Consulter

2017

Subarachnoid Hemorrhage Severely Impairs Brain Parenchymal Cerebrospinal Fluid Circulation in Nonhuman Primate.

Subarachnoid hemorrhage (SAH) is a devastating form of stroke with neurological outcomes dependent on the occurrence of delayed cerebral ischemia. (…)

Consulter

2016

Proportion of single-chain recombinant tissue plasminogen activator and outcome after stroke.

To determine whether the ratio single chain (sc)/(sc + 2 chain [tc]) recombinant tissue plasminogen activator (rtPA) influences outcomes in (…)

Consulter

2016

Hyperfibrinolysis increases blood-brain barrier permeability by a plasmin- and bradykinin-dependent mechanism.

Hyperfibrinolysis is a systemic condition occurring in various clinical disorders such as trauma, liver cirrhosis, and leukemia. Apart from increased (…)