Publications Le 07 Déc 2020 Publications Filtrer nos publications par : Année20232022202120202019201820172016201520142013201220112010200920082007200620052004200320022001 2009 Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic. Thrombolysis with tissue-type plasminogen activator (tPA) is used for the treatment of patients with acute ischemic stroke. However, a growing (…) Consulter 2008 Anti-Mullerian-hormone-dependent regulation of the brain serine-protease inhibitor neuroserpin. The balance between tissue-type plasminogen activator (tPA) and one of its inhibitors, neuroserpin, has crucial roles in the central nervous (…) Consulter 2008 Tissue-type plasminogen activator is a regulator of monocyte diapedesis through the brain endothelial barrier. Inflammatory cell trafficking into the brain complicates several neurological disorders including multiple sclerosis. Normally, reliable brain functioning is maintained and (…) Consulter 2008 HtrA1-dependent proteolysis of TGF-beta controls both neuronal maturation and developmental survival. Transforming growth factor-beta (TGF-beta) signalling controls a number of cerebral functions and dysfunctions including synaptogenesis, amyloid-beta accumulation, apoptosis and excitotoxicity. (…) Consulter 2008 Toward safer thrombolytic agents in stroke: molecular requirements for NMDA receptor-mediated neurotoxicity. Current thrombolytic therapy for acute ischemic stroke with tissue-type plasminogen activator (tPA) has clear global benefits. Nevertheless, evidences argue that (…) Consulter 2008 Improving outcome after stroke: overcoming the translational roadblock. Stroke poses a massive burden of disease, yet we have few effective therapies. The paucity of therapeutic options stands contrary (…) Consulter Pages: First Page12345678910111213141516171819202122232425262728293031323334353637383940414243444546474849505152535455565758596061626364656667686970717273747576777879808182838485Last PageLoad More Retour