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Le 07 Déc 2020

Publications

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2009

Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic.

Thrombolysis with tissue-type plasminogen activator (tPA) is used for the treatment of patients with acute ischemic stroke. However, a growing (…)

Consulter

2008

Anti-Mullerian-hormone-dependent regulation of the brain serine-protease inhibitor neuroserpin.

The balance between tissue-type plasminogen activator (tPA) and one of its inhibitors, neuroserpin, has crucial roles in the central nervous (…)

Consulter

2008

Tissue-type plasminogen activator is a regulator of monocyte diapedesis through the brain endothelial barrier.

Inflammatory cell trafficking into the brain complicates several neurological disorders including multiple sclerosis. Normally, reliable brain functioning is maintained and (…)

Consulter

2008

HtrA1-dependent proteolysis of TGF-beta controls both neuronal maturation and developmental survival.

Transforming growth factor-beta (TGF-beta) signalling controls a number of cerebral functions and dysfunctions including synaptogenesis, amyloid-beta accumulation, apoptosis and excitotoxicity. (…)

Consulter

2008

Toward safer thrombolytic agents in stroke: molecular requirements for NMDA receptor-mediated neurotoxicity.

Current thrombolytic therapy for acute ischemic stroke with tissue-type plasminogen activator (tPA) has clear global benefits. Nevertheless, evidences argue that (…)