Publications

Le 07 Déc 2020

Publications

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2016

The "inflammatory penumbra" in ischemic stroke: From clinical data to experimental evidence.

The objective of the present review is to provide an overview of the available clinical and preclinical data supporting the (…)

Consulter

2016

The story of an exceptional serine protease, tissue-type plasminogen activator (tPA).

The only acute treatment of ischemic stroke approved by the health authorities is tissue recombinant plasminogen activator (tPA)-induced thrombolysis. Under (…)

Consulter

2015

Impacts of tissue-type plasminogen activator (tPA) on neuronal survival.

Tissue-type plasminogen activator (tPA) a serine protease is constituted of five functional domains through which it interacts with different substrates, (…)

Consulter

2016

Epidural Cortical Stimulation as a Treatment for Poststroke Aphasia: A Systematic Review of the Literature and Underlying Neurophysiological Mechanisms.

Nearly 15 million people suffer from stroke every year worldwide, with about 20% of the survivors retaining chronic aphasic symptoms. (…)

Consulter

2016

Tissue Plasminogen Activator Expression Is Restricted to Subsets of Excitatory Pyramidal Glutamatergic Neurons.

Although the extracellular serine protease tissue plasminogen activator (tPA) is involved in pathophysiological processes such as learning and memory, anxiety, (…)

Consulter

2016

Stressed neurons protect themselves by a tissue-type plasminogen activator-mediated EGFR-dependent mechanism.

In the central nervous system, tissue-type plasminogen activator (tPA) has been associated with both pro-death and prosurvival actions on neurons. (…)