Relationship between brain volumetric changes and interim drinking at six months in alcohol-dependent patients.
Auteur : Segobin SH, Chételat G, Le Berre AP, Lannuzel C, Boudehent C, Vabret F, Eustache F, Beaunieux H, Pitel AL
Année : 2014
Journal : Alcohol Clin Exp Res 1530-0277
PubMed Id : 24483366
Chronic alcohol consumption results in brain damage potentially reversible with abstinence. It is however difficult to gauge the degree of recovery of brain tissues with abstinence since changes are subtle and a significant portion of patients relapse. State-of-the-art morphometric methods are increasingly used in neuroimaging studies to detect subtle brain changes at a voxel level. Our aim was to use the most refined morphometric methods to observe in alcohol dependence the relationship between volumetric changes and interim drinking over a 6-month follow-up.