Intestinal MAdCAM-1 imaging as biomarker for prognostic in murine models of multiple sclerosis.

Le 01 Mai 2024

Auteur : Baudron E, Martinez de Lizarrondo S, Gauberti M, Delaunay-Piednoir B, Fournier AP, Vivien D, Docagne F, Bardou I

Année : 2024

Journal : Brain Behav Immun 1090-2139

PubMed Id : 38604270

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system. Recent evidence suggests that lymphocyte trafficking in the intestines could play a key role in its etiology. Nevertheless, it is not clear how intestinal tissue is involved in the disease onset nor its evolution. In the present study, we aimed to evaluate intestinal inflammation dynamic throughout the disease course and its potential impact on disease progression.