Brain and cognitive correlates of sleep fragmentation in elderly subjects with and without cognitive deficits.
Auteur : André C, Tomadesso C, de Flores R, Branger P, Rehel S, Mézenge F, Landeau B, Sayette V, Eustache F, Chételat G, Rauchs G
Année : 2019
Journal : Alzheimers Dement (Amst) 2352-8729
PubMed Id : 30788411
Sleep disturbances are increasingly recognized as a risk factor for Alzheimer’s disease. However, no study has assessed the relationships between objective sleep fragmentation (SF) and brain and cognitive integrity across different cognitive stages, from cognitively unimpaired elderly subjects to patients with subjective cognitive decline and/or mild cognitive impairment.