Beta-amyloid burden in the temporal neocortex is related to hippocampal atrophy in elderly subjects without dementia.
Le 02 Nov 2021
Auteur : Bourgeat P, Chételat G, Villemagne VL, Fripp J, Raniga P, Pike K, Acosta O, Szoeke C, Ourselin S, Ames D, Ellis KA, Martins RN, Masters CL, Rowe CC, Salvado O,
Année : 2010
Journal : Neurology 1526-632X
PubMed Id : 20065247
To investigate whether global and regional beta-amyloid (Abeta) burden as measured with 11C Pittsburgh compound B (PIB) PET is associated with hippocampal atrophy characterized using MRI in healthy controls and patients with amnestic mild cognitive impairment (aMCI) or Alzheimer disease (AD).
